Calamine is a mixture of zinc oxide and ironoxide that is used in many skincare products as a skin protectant, absorbent,and pacifying agent. It's also the name of an over-the-counter (OTC)lotion or cream that can help relieve minor skin irritations like itching,pain, and discomfort. Calamine can also help dry out oozing skin andprotect the skin. It can be used to treat conditions such as: Bug bites,Chickenpox, Poison ivy, Shingles, Swimmer's itch, Heat rash, Scabies, Chiggerbites, Acne, and Hives.