Hyaluronic acid is a completely transparent, non-adhesive, water-soluble and grease-free acid mucopolysaccharide. Its molecular weight is between a few hundred thousand to millions, and it makes up the dermis layer of the skin. Its unique molecular structure and physicochemical properties has many important physiological functions inside the body, such as lubricating joints, adjusting vascular permeability, adjusting proteins, diffusing and transporting water electrolytes, and promoting wound healing. Hyaluronic acid has a unique water retention effect and has the best known natural moisturizing properties, making it the ideal natural moisturizer. Hyaluronic acid is an essential drug in ophthalmic "sticky surgeries. It is used in cataract surgery, in which its sodium salt remains in the anterior chamber to maintain depth in the anterior chamber and ensure a clear surgical view. It reduces the occurences of postoperative inflammation and complications, thus improving the vision-correcting effects of the surgery. It is also used in complicated retinol detachment surgery. Hyaluronic acid has a low molecular weight and is considered the ideal natural moisturizing agent, so it is used as an additive in high-end makeup and as a moisturizer in creams, gels, lotions, masks, and serums. It is also used medically as a moisturizer to improve moisture retention and lubrication, and it also expands capillaries and improves skin health. For example, hyaluronic acid with a low molecular weight can be used as a lubricant in surgeries (such as knee surgery), while those with high molecular weight can be used as surgical lubricant and as a substitute for vitreous in ophthalmic surgery.
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